Deep learning model predicts how individual cells influence disease outcomes

A computational method called scSurv, developed by researchers at Institute of Science Tokyo, links individual cells to patient outcomes using widely available bulk RNA sequencing data. The approach ...
Baylor College of Medicine

Single-cell RNA sequencing of bone metastases reveals distinct immune archetypes

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not well understood. In a new study published in Cell Genomics, researchers at ...
Technology Networks

Single-Cell Atlas Maps Sea Urchin Embryo Development

A single-cell RNA atlas maps sea urchin development, revealing rare neuronal lineages and gene activity across stages, and enabling intuitive exploration through a public database.
ascopubs.org

Single-cell RNA sequencing atlas of intestinal injury induced by different clinical treatments in colorectal cancer patients.

Out of touch: Understanding the frequency and trajectory of chemotherapy-induced neuropathy peripheral (CIPN) in breast cancer survivors. Incidence of ocular toxicities in patients with ...
eLife

Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associations

Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles ...

Genovis AB: Genovis and Single Cell Discoveries Enter Strategic Partnership for Large-Scale Transcriptomics Analyses

Genovis AB, a leading provider of innovative enzyme technologies, today announces a strategic partnership with Single Cell Discoveries to broaden the application of the SEQURNA® Thermostable RNase Inh ...
Technology Networks

Single-Cell Analysis Uncovers Fibrosis Mechanism in Crohn’s Disease

Researchers discovered immune cell aggregates in the gut may signal blood vessel cells and fibroblasts to produce excess collagen, driving fibrosis in Crohn’s disease. The findings could guide ...

From pathology image to biological discovery: LazySlide uses foundation models to connect tissue images and RNA data

Microscopic images of human tissue are a cornerstone of biomedical research and clinical diagnostics. Yet despite their ...

HIV-seq tool finds active reservoir cells during therapy

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and ...